| Symbol | Company | Weighting |
|---|---|---|
| SRRK | SCHOLAR ROCK HLDG CORP USD | 3.95% |
| AKRO | AKERO THERAPEUTICS INC | 2.70% |
| NTRA | NATERA INC | 2.61% |
| RYTM | RHYTHM PHARMACEUTICALS INC | 2.59% |
| ARGX | ARGENX SE ADR | 2.58% |
| RNA | AVIDITY BIOSCIENCES INC | 2.40% |
| ISRG | INTUITIVE SURGICAL INC | 2.33% |
| ITCI | INTRA-CELLULAR THERAPIES USD | 2.19% |
| NUVL | NUVALENT INC | 2.19% |
| TARS | TARSUS PHARMACEUTICALS | 2.08% |
| INSP | INSPIRE MEDICAL SYSTEMS, INC. | 1.98% |
| DNLI | DENALI THERAPEUTICS INC. | 1.98% |
| BSX | BOSTON SCIENTIFIC | 1.97% |
| ALKS | ALKERMES INC | 1.96% |
| PCVX | VAXCYTE INC | 1.93% |
| MCK | MCKESSON CORP | 1.92% |
| SYK | STRYKER CORP | 1.91% |
| LNTH | LANTHEUS HOLDINGS INC | 1.86% |
| RARE | ULTRAGENYX PHARMACEUTICAL INC | 1.86% |
| UNH | UNITEDHEALTH GROUP INC | 1.82% |
| ASND | ASCENDIS PHARMA A/S DKK 1.0 ADR | 1.78% |
| XNCR | XENCOR INC. | 1.78% |
| DYN | DYNE THERAPEUTICS, INC. | 1.76% |
| TEVA | TEVA PHARMACEUTICAL INDS LTD | 1.74% |
| EXAS | EXACT SCIENCES CORP | 1.72% |
| ZTS | ZOETIS INC | 1.64% |
| SNY | SANOFI- AVENTIS- ADR | 1.63% |
| VRTX | VERTEX PHARMACEUTICALS INC | 1.62% |
| HCA | HCA HOLDINGS INC | 1.61% |
| BDX | BECTON DICKINSON & CO | 1.53% |
| IONS | IONIS PHARMACEUTICALS INC | 1.51% |
| NBIX | NEUROCRINE BIOSCIENCES INC | 1.48% |
| AMGN | AMGEN CORP | 1.46% |
| DHR | DANAHER CORP | 1.46% |
| CRL | CHARLES RIVER LABORATORIES INT INC | 1.45% |
| IMVT | IMMUNOVANT INC | 1.45% |
| SRPT | SAREPTA THERAPEUTICS INC | 1.41% |
| AZN | ASTRAZENECA PLC-ADR | 1.39% |
| AVTR | AVANTOR, INC. | 1.37% |
| BMRN | BIOMARIN PHARAMCEUTICAL INC | 1.36% |
| CYTK | CYTOKINETICS INC | 1.35% |
| WST | WEST PHARMACEUTICAL SERVICES INC | 1.35% |
| EW | EDWARDS LIFESCIENCES CORP | 1.32% |
| SNDX | SYNDAX PHARMACEUTICALS, INC. | 1.31% |
| ARVN | ARVINAS INC USD | 1.31% |
| NVO | NOVO NORDISK A/S | 1.30% |
| LLY | ELI LILLY CORP | 1.30% |
| IDXX | IDEXX LABS CORP | 1.28% |
| REGN | REGENERON PHARMACEUTICALS | 1.28% |
| VKTX | VIKING THERAPEUTICS, INC. | 1.28% |
| ELV | ELEVANCE HEALTH INC | 1.24% |
| APLS | APELLIS PHARMACEUTICALS INC | 1.23% |
| ARWR | ARROWHEAD PHARMACEUTICALS INC | 1.23% |
| MRK | MERCK & CO. NEW | 1.23% |
| TMO | THERMO FISHER SCIENTIFIC INC | 1.22% |
| BIIB | BIOGEN INC | 1.08% |
| TNDM | TANDEM DIABETES CARE INC | 1.08% |
| ACHC | ACADIA HEALTHCARE CO INC | 0.95% |
| DXCM | DEXCOM INC | 0.90% |
| KURA | KURA ONCOLOGY INC | 0.80% |
Read a prospectus and summary prospectus (if available) carefully before investing. It contains the investment objective, risks charges, expenses and the other information, which should be considered carefully before investing. To obtain a prospectus and summary prospectus (if available) click here or call 800.820.0888.
Investing involves risk, including the possible loss of principal.
Guggenheim Investments represents the following affiliated investment management businesses of Guggenheim Partners, LLC: Guggenheim Partners Investment Management, LLC, Security Investors, LLC, Guggenheim Wealth Solutions, LLC, Guggenheim Funds Distributors, LLC, Guggenheim Funds Investment Advisors, LLC, Guggenheim Corporate Funding, LLC, Guggenheim Partners Europe Limited, Guggenheim Partners Japan Limited, and GS GAMMA Advisors, LLC. Securities offered through Guggenheim Funds Distributors, LLC.
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